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Beyond their supportive functions for the brain, they also hold significant potential as therapeutic target under neurodegenerative conditions 124

Molecular mechanisms that confer antibacterial drug resistance

This type of ROS alters the mitochondrial DNA, resulting in deleterious changes in important proteins that form the enzyme complexes mentioned above, thereby generating the phenomenon known as mitochondrial dysfunction, which is responsible for increased synthesis of free radicals
PMCID: PMC5075670

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doi:10.12816/0006054 [29] Huiberts LM, Smolders KCHJ
