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The Journal of Phytopharmacology

Alcohol Clin Exp Res 37:668674

You can develop a resistance to others, like medications that increase dopamine in the brain

In adult brain, the carbons from the acetyl moiety can be used to synthesize fatty acids, which are preferentially incorporated into structural lipids, rather than oxidized via -oxidation [45, 56]
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This means that they both cannot be made within the body and must be consumed in the diet