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Surgical Ligation The shunting vessel is identified by midline laparotomy and narrowed or completely occluded by a nonabsorbable ligature
If human trials with the compound show safety and efficacy, NNMT inhibitors like 5-amino-1MQ could serve to prevent and/or slow age-related muscle deterioration in humans, a tantalizing prospect
Using experimental model of CKD-induced muscle atrophy in mice, Wang et al
doi: 10.1016/j.mtbio.2023.100654
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