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[CrossRef] [PubMed] [Google Scholar] Missed opportunity to diagnose subungual melanoma: Potential pitfalls

The benefits, adverse events, drug interactions, and safety of St John's wort ( Hypericum perforatum ): the implications with regard to the regulation of herbal medicines

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Importantly, the so-called Hook effect, also known as the prozone effect, antibody excess, or the prozone phenomenon, occurs when the target antigen/antibody is in greater concentrations than those of the capture antibodies and vice versa (i.e., when the capture antibodies are very low levels compared to the target), and it can trigger false-negative test results in several assay techniques, including one-step immunometric assays, TIAs, NMAs, ELISAs, LFIAs, and other immunochromatographic assays [1156,1160,1189,1190,1191]

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