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Hydroxy B12 shots will be safer

Tiredness / lethargy Depression Hair loss Pins & needles Numbness in the hands or feet Tremors or palsies Palpitations Recurrent headaches Dizziness Slower digestion / weight gain Irritability Mood swings Confusion Forgetfulness Fogginess Psychosis Hallucinations or delusion Anxiety/Panic attacks Onset of dementia Hormonal imbalances or worsened menopause symptoms What are contra-indications to having Vitamin B12 intramuscular injections

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High B12 from supplements or injections rarely causes concern

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The honest research caveat is that "theoretically additive" is not "experimentally additive" and a researcher who needs to claim synergy must run the combination versus the components in their own model