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doi: 10.1016/j.aca.2025.344144 Summary Keywords aquaculture microbiome, climate resilience, CRISPR engineering, disease resistance, fecal microbiota transplantation (FMT), multi-omics, probiotics, sustainable aquaculture Citation Tayyab M, Zhao Y and Zhang Y (2025) Microbiome engineering to enhance disease resistance in aquaculture: current strategies and future directions