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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (which can be caused by ingestion of corrosives, extensive tumors, and conditions associated with gastric atrophy, such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy) Structural lesions leading to vitamin B 12 deficiency, including regional ileitis, ileal reactions, and malignancies Competition for vitamin B 12 by intestinal parasites or bacteria

Vaccines 434:1882 Zeng J, Wang J, Wu J, Deng R, Zhang L, Chen Q, Wang J, Jin X, Gui S et al (2023) A novel antimicrobial peptide M18 targets the lysosomal pathway to inhibit autolysosome formation and promote apoptosis in liver cancer cells

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