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Despite the wealth of evidence that characterizes the metabolically unfavorable changes in hepatic pathways linked to estrogen deficiency (8, 13), the potential for estrogen-based hormone replacement therapy (HRT) to limit the development of MASLD has not been rigorously tested

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Knoop KA, McDonald KG, McCrate S, et al

It was the purpose of the present investigation to examine the effects of 28 days of varying GPLC dosing on anaerobic work capacity and lactate accumulation

The supernatant was processed according to the instructions, and the absorbance values were detected at 490 nm using a spectrophotometer Multiskan FC (ThermoFisher Scientific Inc., Waltham, MA, United States)

For negative controls, ALDH activity was blocked with 15 M of the selective ALDH inhibitor DEAB