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This also results in the opening of the mPTP leading to uncontrolled ROS production and disrupted synaptic maturation causing autistic behaviors [127]

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De novo resveratrol production through modular engineering of an Escherichia coli-Saccharomyces cerevisiae co-culture

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Furthermore, excessive zinc disrupts zinc finger protein function by saturating binding sites, leading to protein misfolding and loss of DNA-binding specificity, which may further dysregulate immune gene expression