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This reduces oxidative DNA damage within melanocytes, diminishing the triggers that upregulate melanin production in the first place

Peroxynitrite can initiate DNA damage, leading to the stimulation of a nuclear enzyme, poly (ADP-ribose) synthase (PARS), which causes a decrease in cellular energy levels and leads to cell death

Fish Shellfish Immunol 49:427435 Stec DE, Gordon DM, Hipp JA, Hong S, Mitchell ZL, Franco NR et al (2019) Loss of hepatic PPAR promotes inflammation and serum hyperlipidemia in diet-induced obesity

Role of tryptophan 161 in catalysis by human manganese superoxide dismutase

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Clin Pharmacokinet 51:553572 Ricciolini R, Scalibastri M, Kelleher JK, Carminati P, Calvani M, Arduini A (1998) Role of acetyl-l-carnitine in rat brain lipogenesis: implications for polyunsaturated fatty acid biosynthesis