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For instance, hydrogenosomal enzymes, such as hydrogenase and pyruvate-ferredoxin oxidoreductase (PFOR) [18], are seen as appropriate targets for new drugs, either because they are not found in host cells or because their sequences/structures are not conserved

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Hepatic fibrosis, or the excessive collagen deposition in the liver (see next section), is associated with oxidative stimuli and cell death