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It should be administered in the morning as well

8 9 The consequences of mild or subclinical vitamin B 12 deficiency are less clear but it has been shown to be associated with decreased cognitive performance in both the elderly and children

Serum B12 alone has recognised limitations and does not always accurately reflect tissue-level B12 status

Next Generation Radiation Medicine: Putting Biology and Technology to Work
Modifier -50 is not appropriate in this case
Notably, it can lead to a false-positive pregnancy test due to its molecular similarity to endogenous pregnancy HCG, which is the target of standard hCG immunoassays