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The paper also found that cancer cell lines showed a different response, appearing to rely more on an alternative lengthening of telomeres (ALT) mechanism rather than telomerase activation directly
Therapeutic opportunities and challenges Genetic screens carried out so far in GBM have enabled the identification of genes driving metabolism, growth and cell cycle, DNA-repair and immortality pathways

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Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges

albicans by activating Cyr1p (Xu et al., 2008)
