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While acute alcohol use has been shown to impair production of proinflammatory cytokines such as TNF- and IL-1, which may predispose patients to pneumonia, chronic alcohol use has associated with increased levels of proinflammatory cytokines, such as TNF-, IL-1, and IL-6, in both human and animal studies

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IL-4, IL-5, and IL-13 levels in BALF
