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SAMe pretreatment protected against liver injury and prevented the fall in GCLC and GCLM expression and GSH level

Venditti et al., 2013)

One activates a single receptor pathway

In conclusion, while Zahra et al.s clinical trials reported low tolerance to ketogenic diet among patients, findings from preclinical models demonstrate that a 4:1 ketogenic diet can improve response to radiation therapy without increasing toxicity

Additionally, we focus on the limitations of mitochondrial therapy in clinical applications, and discuss potential future research directions for mitochondrial therapy