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When we experience stress, the adrenals respond by releasing hormones such as cortisol and adrenaline, which have effects including increasing your blood pressure and your heart rate

doi: 10.1016/j.redox.2020.101791 27 LazaropoulosM.DongY.ClarkE.GreeleyN

Altered ATP7B expression in cancer is also associated with tumor progression and drug resistance

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While GSH has no known role in these enzymes, general oxidative stress can impair protein stability