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Statements Author contributions MS, SG, IK, and SS: conceptualization and methodology

Low B12 levels have been linked to mood swings, irritability, and even symptoms of depression

Schoenenberger & Monnier, Progress in Neurobiology (1977) Foundational studies characterising DSIPs role in sleep modulation and associated neurochemical mechanisms

Typically, the results of Mesotherapy last for 12-18 months

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Symptom Journaling: This is crucial for tracking subjective improvements in energy, mood, brain fog, and pain