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3 Vincze G, et al

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In another rat model of DN, ALA administration for 5 weeks attenuated proteinuria by downregulating renal cortical expression of fibrotic markers, transforming growth factor-beta1 (TGF-1) and fibronectin, via inhibition of p38 MAPK signaling pathway (Lee et al., 2009), and inhibited proliferation of high glucose-exposed human mesangial cells via the same mechanism (Zhang et al., 2021) (Fig

PC metabolism generates potent bioactive lipid messengers most notably lysophosphatidic acid (LPA) and platelet-activating factor (PAF) that coordinate key aspects of tumor progression and intercellular communication within the TME

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[DOI] [PubMed] [Google Scholar] 57.Skouta R, et al