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Collectively, these findings reveal that miRNAs from different sources and with distinct functions finely regulate macrophage polarization, forming a complex molecular regulatory network in the pathogenesis of PAH
It accelerates blood vessel formation (angiogenesis), modulates inflammatory pathways, and enhances collagen synthesis, all of which are crucial for tissue recovery
In addition, higher drug concentration was also noticeable in the brain areas
Si-Tayeb et al., 2010
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