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The most commonly reported adverse events were mild-to-moderate headache and gastrointestinal effects including flatulence and mild diarrhea

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Among all of the analyzed vaccine candidates in this study, BB0172-derived peptide, recombinant OspA along with meningococcal outer membrane vesicles, recombinant P66, recombinant VISE, and chimeric OspA revealed stronger positive effect ( Figure 4 )