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Consequently, any factor inhibiting SLC7A11 function or downregulating its expression leads to intracellular GSH depletion, thereby depriving GPX4 of its essential substrate and ultimately triggering irreversible ferroptosis

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NaBPC157 (10.0 g/kg i.p.) or saline (5.0 ml/kg i.p.) was given 1 hour before the treatment of ethanol

Chemical Information: BPC-157

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