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Comet assay for DNA damage Cells in culture were untreated (DMSO, control) or treated with R001 at the indicated concentrations for 24 h, or in the case of H 2 O 2 (400 M), cells were treated for 1 h

Indications: Depression typically for patients who do not respond to SSRIs, NDRIs and other 2nd or 3rd generation antidepressants Neuropathic (Chronic) pain Neuropathic pain does not typically respond to classic analgesics, or opioids

Laboratory test results showed that the WBC count was 7.5 10 9 , neutrophil was 58.5%, Hb was 136 g/L, ALT was 26 U/L, AST was 21 U/L, TP was 79.8 g/L, LDH was 165 U/L, -HBDH was 144 U/L, creatinine was 70 mol/L, urea was 3.83 mmol/L, 24-hour urine creatinine was 16290 mol, 24-hour urine protein was 0.51 g, 24-hour urine beta 2-microglobulin was 0.39 mg, urinary N-Acetyl B-D-glucosamine was 22.56 U, 24-hour urine 1-microglobulin was 12.38 mg, 24-hour urine nitrogen was 259.65 mmol, and the ratio of mercury to creatinine in the urine was 4294.5 g/g