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Further, in Nrf2 knockout mice, GPx-1 expression is downregulated in lung after exposure to cigarette smoke (330)

This finding is also supported by several genetic variations seen in ASD patients related to the transmethylation/transsulfuration pathway, where glutathione is one of the byproducts (1618)

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[DOI] [PubMed] [Google Scholar] 107.Peng H., Xu J., Yang X.P., Dai X., Peterson E.L., Carretero O.A., Rhaleb N.E