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Cancer Chemother Pharmacol 71:11151130 Acipayam C, Bayram I, Daglioglu K, Doran F, Yilmaz S, Sezgin G, Totan Ate B, Ozkan A, Tanyeli A (2013) The protective effect of hesperidin on methotrexate-induced intestinal epithelial damage in rats: an experimental study