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19 It is also now clear that CYP-derived EETs also protect the heart against acute ischemia-reperfusion injury and chronic non-ischemic cardiomyopathy and hypertension

Among these, lisdexamfetamine (LDX) has gained interest for its mechanism of action and therapeutic versatility for the treatment of attentiondeficit/hyperactivity disorder (ADHD) and binge eating disorder (BED) [1]

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Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia

Three priority directions emerge: development of validated biomarkers for preoperative risk stratification, incorporation of pharmacogenomic tools to individualize anesthetic selection, and optimization of neuroprotective agents with improved bloodbrain barrier penetration