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Miyazaki M, Bruggink SM, Ntambi JM (2006) Identification of mouse palmitoyl-CoA delta 9 desaturase

Barbier-Torres, L

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Increasing total muscle carnitine content in healthy humans may support physiological function by reducing muscle glycolysis and increasing glycogen storage, fat oxidation, and work output.[5,6] A randomized, placebo-controlled human subject study suggested that carnitine can improve exercise tolerance and inspiratory muscle strength, as well as reduce lactate production.[7] A six-month, randomized, double-blind, placebo-controlled study of 50 children suggested that oral supplementation with L-carnitine helped support normal carnitine levels in the body with statistically significant positive effects on support of lung function.*[8] The role of carnitine in normal fertility has been investigated with meta-analysis of nine randomized controlled trials suggesting that carnitine may be effective in improving pregnancy rate and sperm kinetics, though further research is warranted.[9] In some individuals, carnitine supplementation may support cardiovascular health and triglyceride and HDL levels already within the normal range.*[10,11] Carnitine participates in cell volume and fluid balance, liver lipid metabolism, and antioxidant activity