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In addition to -synuclein, there is mounting evidence implicating other genetic mutations such as in Parkin, leucine-rich repeat kinase 2 (LRRK2) and DJ-1, alongside environmental factors (including exogenous neurotoxins, age and diet) as potential contributors to the etiology of PD (99,100)

[Abstract] Int J Oral Sci
Koutmos M, Gherasim C, Smith JL, Banerjee R (2011) Structural basis of multifunctionality in a vitamin B 12 -processing enzyme
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3 As in beetroot juice, nitrates in beetroot powder ultimately increase nitric oxide production by cells lining blood vessels