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For example, it is known that ferroptosis and other types of cell deaths (necroptosis and apoptosis) occur concurrently following ischemic and traumatic brain injury (Zille et al., 2017

Vit-E could effectively prevent ferroptosis by reducing the Fe 3+ center to inactive Fe 2+ in lipoxygenase (LOX), thereby inhibit enzyme activity of LOX

Most researchers prefer the first option for simplicity

10.1021/acs.analchem.0c00985 47 LuoY.GaoF.ChangR.ZhangX.ZhongJ.WenJ.et al (2021)

Terpenoids from quinoa reverse drug resistance of colon cancer by upregulating miR-495-3p

Although effective, these medications often present such side effects as skin rashes, fever, arthralgia, liver toxicity, and agranulocytosisan extreme decline in white blood cell count-that preclude their long-term use in certain patients (Mishra et al