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Recent investigations have revealed an augmented glucose uptake in microglia in AD in both AD mice and patients

The inflammation is maintained by several mediators (e.g., by IL-23, IL-17, or GM-CSF) and signaling pathways (e.g., through the JAK/STAT signaling route) (129)

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Study design After the diagnosis was confirmed, the patients were divided into two groups: the IDB treatment group and control group: (1) IDB group: patients took 30 mg of oral IDB three times a day for 6 months