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Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

Aseptic simply means being free from contamination caused by harmful bacteria, viruses, or other microorganisms, or in another word, sterile
Although, generally, animal tumor models only partially share a similarity with human disease, the use of this model has achieved general acceptance because of its possible usefulness when applied in anti-tumor agent research

Enhancement of NETosis by ACE2-cross-reactive anti-SARS-CoV-2 RBD antibodies in patients with COVID-19

Danese S, Semeraro S, Marini M, et al

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