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In the oral cavity, LL-37 (a cathelicidin), histatins (salivary peptides), and human beta-defensins (HBDs) are produced continuously but their expression is suppressed by chronic inflammation, poor nutrition, and aging, contributing to periodontal disease progression

Future studies will further elucidate the currently unrecognized metabolic landscape of TLS

Djeridane et al

The GALT is an incredibly complex and diverse immune network constituting around 70% of the immune system and involving a variety of cell types and tissue structures [36, 115]
3E, 3F)
