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Description
A Multicenter Study of the Effects of Vitamin B12on Sleep-Waking Rhythm Disorders: In Shizuoka Prefecture

So, what you posted is a report that has not been subjected to randomized double-blind placebo based controlled study which from my reading takes about 6-7 years to develop and complete

[27]Celi GEA, Grato PL, et al

Topical GHK-Cu The topical route is the most studied and has the strongest human evidence base
[DOI] [PubMed] [Google Scholar] 167.Friedman SL, Roll FJ, Boyles J, Arenson DM, Bissell DM

Cell 120, 437447
