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doi: 10.1111/j.1365-2362.1991.tb01808.x

Given that some mutant enzymes retain low-level FAD-binding capacity, a gene + high-dose riboflavin synergy strategy has been proposed: in AIFM1 encephalopathies, low-level AAV transduction re-establishes baseline protein expression, while daily riboflavin doses above 400 mg act as a molecular chaperone to stabilize FAD binding a regimen shown to improve ICARS scores and neuroimaging outcomes (54, 75)

Glutathione helps transport amino acids around in addition to expelling toxic compounds like heavy metals from your body

Expert Opinion on Drug Metabolism & Toxicology

Those real outcomes drive our conservative, measured approach

Multiple mechanisms of action have been considered, including: 1) anti-inflammatory properties of omega-3 fatty acids, which reduce cardiac remodelling caused by excessive interstitial fibrosis and systemic inflammatory process leading to cardiac cachexia