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The demand for GSH skyrockets during pregnancy to: Protect the delicate, rapidly dividing cells of the fetus from genetic mutations

2.2.3 8-hydroxy-2-deoxyguano-sine (8-OHdG) Reactive oxygen radicals attack the carbon atom at the 8-position of the guanine base in the DNA molecule, producing the oxidation product 8-OHdG

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Temperature cycling, repeatedly moving between refrigerator and room temperature, accelerates degradation beyond what either constant temperature would cause

Striepen, B

Energy substrates and metabolic characteristics of microglia Glucose is the primary energy source for microglial survival and function, with hypoxic glucose deprivation leading to microglial cell death (Kacimi et al., 2011