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However, stacking an aggressive compound with known kidney toxicity with additional peptides that also need to be cleared by the kidneys would logically increase renal burden

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Purcell, B

Unexpectedly, subjects receiving CNTF in clinical trials for this indication experienced weight losses of 10--15%, prompting researchers to consider using CNTF to treat obesity [71]

It is frequently used alongside regenerative options such as platelet-rich plasma and other biologic therapies to help optimize overall outcomes