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Discussion Significance of the study To our knowledge, this is the most comprehensive network meta-analysis comparing the efficacy of SL, IM, and oral routes of administration of vitamin B12 in patients with vitamin B12 deficiency

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Just like if you have a problem with MTHFR and inadequate natural folate, problems occur when inadequate natural or coenzyme vitamin B12 exists

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Leptin is usually transported across the blood-brain barrier by a specialized leptin-transporter that is impaired in obesity [17]

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Pregnant or breastfeeding women should receive B12 supplementation only under the guidance of an obstetrician not at a med spa

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On the downside, vitamin B12 injections can be quite painful

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