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The randomness in the assignment of participants to treatments reduces selection bias and allocation bias, balancing both known and unknown prognostic factors, in the assignment of treatments

The control incubations with DTT and diamide are utilized to calculate from the I 405 / I 488 ratio the degree of roGFP2 oxidation (OxD)
Invest Cell Pathol 2(3):195216 Fuchs CD, Trauner M (2022) Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology

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Third, and perhaps most importantly, self-administration removes the clinical feedback loop