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An example of a purification monitored by SDS-PAGE is shown in Fig

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doi:10.1081/CBI-120038597

Initially, 2-3 sessions per week may be recommended, followed by maintenance treatments once a month after achieving desired results

Although the early endeavours of targeting matrix metalloproteinases were not successful in clinical trials, metalloproteinases are still preferred as one of a potential therapeutic target, considering their importance in disease progression 37