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More recently, the first complete genome of a GT1g isolate derived from a Spanish patient was published 77

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Besides, ECs-monocytes interactions irritated by Apo CIII may relate to pertussis toxin (PTX)-sensitive G protein and phosphatidylcholine-specific phospholipase C (PC-PLC) that participates in PKC activation and further activates nuclear factor-kappaB (NF-B) and upregulates 1-integrin expression in monocytes 88

High levels of choline, the source of TMAO, were associated with a 2.4-times greater incidence of the disease [29]