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Furthermore, elevated glutathione synthesis in TLS in the kidney is reflected in urinary GSH concentration, suggesting the possibility of its clinical application as a novel biomarker to detect TLS in the kidney

XL184 and XL880 are orally available, non-selective inhibitors, with high binding affinity to both Met and VEGFR and to a lesser extent to other receptor tyrosine kinases such as PDGFR, Ret, Kit, Flt-3 and Tie-2 (Liu et al., 2010)

Ferulic acid mitigates 2-methoxyethanol-induced testicular oxidative stress via combined downregulation of FoxO1, PTEN, and modulation of Nrf2-Hmox1-NQO1 signaling pathway in rats

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Iron-deficient mice failed to develop EAE, while iron overloaded mice developed typical disease [172], suggesting that iron is an important regulator of immune-mediated neurotoxicity