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Sickling provoked by hypertonicity in the renal medulla causes damage that eventually leads to hyposthenuria (the inability to concentrate urine), which increases the propensity for dehydration and its attendant risks

Its role as a reducing agent facilitates the impairment of the parasites metabolic processes, thereby inhibiting its growth and survival

Methods 234 , 3853 (2014)

Creatinine clearance testing is instrumental in monitoring kidney disease progression, and renal failure is often suspected when serum creatinine levels surpass normal thresholds 45,46,47

COVID-19 Induces Body Composition and Metabolic Alterations

New York: Elsevier