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Kidney Dysfunction: High doses over a prolonged period could potentially strain the kidneys, especially in individuals with pre-existing kidney conditions

doi: 10.1016/j.phrs.2021.105753

doi: 10.1038/nrd3031 211 PengHOuyangLLiDLiZYuanLFanLet al

If you have any of these symptoms its a good bet that you are not absorbing the nutrients in your food efficiently

The blood-brain barrier: Bottleneck in brain drug development
Standard oral capsules often give low bioavailability, especially for direct NAD+ or basic glutathione powders
