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Overexpression of the phgdh gene has been observed in colon 126 and gastric cancers 127 , and is associated with poor prognosis, higher tumor grade and larger tumor sizes in CRC 128
doi: 10.1016/j.siny.2009.01.002
The Potential of in Vitro Assays in Unraveling the Role of Metabolism in Drug Induced Liver Toxicity
doi: 10.1016/j.redox.2020.101674 86 OkoyeCNKorenSAWojtovichAP
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