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One study found that even short-term sleep deprivation led to significant reductions in glutathione in certain tissues, due to heightened oxidative load

-amyloid and TAU protein in PD Although the accumulation of -synuclein in Lewy bodies is the defining hallmark of PD, growing evidence suggests that other proteins, most notably -amyloid (A) and tau, also contribute, particularly in cases with cognitive decline

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