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The Authors This article is Open Access: CC BY 4.0 licence (

Supplementary material The Supplementary Material for this article can be found online at: References 1 AgarwalA.BallaJ.AlamJ.CroattA

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doi:10.1111/jog.13462 Bene J, Hadzsiev K, Melegh B

This suggests that deproteinization of EDTA-treated plasma prior to storage is not necessary to prevent spontaneous oxidation of free GSH to GSSG

Of note, it is linked to MAPK signalling and is involved in T-cell activation