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One of the things SAMe and methyl transferases help your body produce is creatine which is important for energy production, especially when you're at the anaerobic threshold (running for a long time, doing a max effort)

250 ZhangX.LiuR.-P.ChengW.-H.ZhuJ.-H

The development of an artificial enzyme, Sul-MPBs, with catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx)-like activities demonstrates promising ROS-scavenging capabilities and protection against hydrogen peroxide-induced mitochondrial dysfunction in vitro [99]

In one study, sulfur nanoparticles increased salt tolerance in field beans by upregulating genes such as ribulose bisphosphate carboxylase large chain-like (RbcL) , ethylene-responsive transcription factor 1 (ERF1) , chlorophyll a-b binding protein of LHCII type 1-like (Lhcb1) , and cell wall invertase I (CWINV1) , while also boosting levels of glycine betaine, proline, and peroxidase enzymes (Khalifa et al., 2024)