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Further investigations reveals that oxidative stress can be categorized as follows ( Figure 1 ): Mitochondrial oxidative stress: Mitochondria, crucial for cellular energy production, are primary targets of oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Xu D., Wu D., Qin M., Nih R., Liu C., Cao Z., et al

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Moreover, the development of selective inhibitors that modulate methionine transporters or key enzymes in the methionine cycle could offer novel therapeutic opportunities while minimizing systemic toxicity

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