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However, current senolytic compounds, many of which are cancer drugs, come with downsides

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Glutathione synthesis plays key roles in the formation of TLS, and a specific metabolic pathway in a limited cell population within TLS determines the outcome of the formation of TLS

PLoS One 9 , e110963 (2014)

The -glutamyl cycle was initially postulated by Meister as a mechanism for amino acid transport (76)

Similarly, both human and mouse pancreatic - and -cells express dopamine and adrenergic receptors, but there are large, species-specific differences in the ratios of dopamine receptors to adrenergic receptors