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In this process, two molecules of GSH are consumed to reduce one molecule of peroxide, yielding GSSG and water (or an alcohol)

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The kinetic data can be best explained by a ternary complex in which PfGrx recruits and activates GSH at the 1st glutathione-interaction site to facilitate the rate-limiting glutathionylation of roGFP2 WT (S 2 ) and its subsequent deglutathionylation in accordance with monothiol mechanism (iii) from Fig

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The false-low b12 phenomenon complicates assessment further

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