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doi:10.1111/j.1524-4725.2005.31732 PMID 16029679 Bissett DL, Miyamoto K, Sun P, Li J, Berge CA

Additionally, certain genetic variations can make it more difficult for some individuals to produce and maintain optimal levels of glutathione

The same authors also found decreased levels of anti-oxidant defense mechanism and, subsequently, more DNA damage [29]